Rabbit Anti Human ROR1 Polyclonal Affinity Purified (PBS with 0.02% sodium azide, 50% glycerol, pH7.3) (Western Blot) from Innovative Research is a polyclonal antibody in a liquid format, buffered in PBS with 0.02% sodium azide, 50% glycerol, pH7.3 This antibody has been purified using Affinity Purified.

More Details:

• Host: Rabbit
• Species: Human,Mouse
• Target: ROR1
• Clonality: Polyclonal
• Purity: Affinity Purified
• Immunogen: Recombinant fusion protein of human ROR1 (NP_005003.2).
• Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles.

This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms.

This product can be used in analytical tools such as Western Blot.

At Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results.

For research use only.